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Effect of Supplemental Oxygen Therapy on Neurocognitive Performance in Healthy Highlanders
Sponsor: University of Zurich
Summary
Exposure to high altitudes, defined as locations above 2500 m, has been shown to cause cognitive alternations due to reduced blood oxygenation (SpO2). However, it remains to be determined whether cognitive changes are present in highlanders living at moderate altitudes (2500 m) and whether cognitive alterations are reversible with supplemental oxygen therapy (SOT).
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-06-18
Completion Date
2026-07-31
Last Updated
2026-06-16
Healthy Volunteers
Yes
Conditions
Interventions
Supplemental oxygen therapy
5 L/min supplemental oxygen therapy administered through nasal canula.
Sham intervention
5 L/min sham intervention administered through nasal canula.