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RECRUITING
NCT07652580

Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma

Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine

View on ClinicalTrials.gov

Summary

The goal of this observational cohort study is to learn how toxin and occupational exposures, germline genetic variation, and immune dysregulation relate to B-cell non-Hodgkin lymphoma among active-duty service members and other Military Health System beneficiaries. The main questions are whether specific exposures and germline variants are associated with B-cell NHL subtype, immune dysfunction, and clinical outcomes. Participants will complete exposure and medical-history surveys, provide biospecimens for immune and genomic testing, and may be followed annually for up to 3 years.

Official title: Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma Across the Military Healthcare System

Key Details

Gender

All

Age Range

4 Years - Any

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2025-05-01

Completion Date

2028-05-01

Last Updated

2026-06-17

Healthy Volunteers

No

Locations (3)

Uniformed Services University of the Health Sciences

Bethesda, Maryland, United States

Walter Reed National Military Medical Center

Bethesda, Maryland, United States

Naval Medical Center Portsmouth

Portsmouth, Virginia, United States