Clinical Research Directory

Inclusion Criteria: 1. Age ≥ 18 years old; 2. Confirmed diagnosis of lower-risk MDS; 3. Platelet ≤ 30×109/L, or \< 50×109/L and accompanied by bleeding events; 4. Baseline liver and kidney functions \<2 ULN; 5. Signed the informed consent form; 6. ECOG 0-2; Exclusion Criteria: 1. History of leukemia or stem cell transplantation, treatment-related MDS or malignant tumors; 2. With splenomegaly or myelofibrosis; 3. Infections or bleeding that cannot be controlled by standard treatment; 4. Any concurrent malignant tumors within the past 5 years, or basal cell carcinoma of the skin at the local site; 5. History of thromboembolic events, heart attack or stroke and current use of anticoagulants; 6. Previously received cyclosporine (CsA) or ATG within 6 months; 7. Previously used IL-11, rhTPO or TPO-RA; 8. Pregnant or lactating women; 9. Participated in other clinical trials within 3 months.