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Risk Factor Assessment for Acute Pulmonary Hypertension Crisis
Sponsor: Peking Union Medical College Hospital
Summary
The goal of this observational study is to learn about pulmonary hypertension crisis (PHC) - a severe, and often fatal complication - in patients with pulmonary hypertension (PH). The main questions this study aims to answer are: What are the clinical and hemodynamic features of PHC, and what underlying pathophysiological mechanisms cause it to develop? Can these features be used to diagnostic PHC, predict who is at risk of developing it or dying from it, and develop targeted prevention and treatment of PHC? A multi-center registry platform and biobank will be established to enroll and follow up patients with PH. Clinical data, hemodynamic measurements, and biological specimen will be collected. Risk prediction and early warning tools of PHC will be developed.
Official title: Research on the Clinical Risk Factor Assessment System for Acute Pulmonary Hypertension Crisis and Its Mortality
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
5000
Start Date
2026-07-01
Completion Date
2029-12-31
Last Updated
2026-06-17
Healthy Volunteers
Not specified
Locations (4)
Guangdong Province People's Hospital
Guangzhou, Guangdong, China
Yan'an Affiliated Hospital of Kunming Medical University
Kunming, Yunnan, China
Peking Union Medical College Hospital
Beijing, China
Shanghai Pulmonary Hospital
Shanghai, China