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Electromyographic Response to Blood Flow Restriction Exercise in Healthy Adults
Sponsor: Universidad de Extremadura
Summary
This study evaluated the immediate neuromuscular response to low-load knee extension exercise performed with and without blood flow restriction in healthy young adults. Blood flow restriction is a training method in which a pressure cuff is applied to the upper part of a limb to partially reduce blood flow during exercise. In this study, each participant completed the same knee extension exercise protocol under two conditions: with blood flow restriction and without blood flow restriction. The blood flow restriction pressure was individualized according to each participant's arterial occlusion pressure. Surface electromyography was used to record the activity of the vastus lateralis muscle during the exercise protocol. Muscle activation was mainly assessed using the root mean square amplitude normalized to a maximal voluntary isometric contraction measured before exercise. Maximal voluntary isometric contraction was also recorded before and after the protocol to explore immediate changes in maximal muscle activation. The study was conducted in healthy adults and aimed to compare the electromyographic response between the blood flow restriction and non-restriction conditions during a standardized low-load exercise task.
Official title: Electromyographic Analysis of Immediate Neuromuscular Response After Low-Load Knee Extension Exercise With and Without Blood Flow Restriction in Healthy Adults
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2026-02-01
Completion Date
2026-04-15
Last Updated
2026-06-17
Healthy Volunteers
Yes
Interventions
Low-load knee extension exercise with blood flow restriction
Participants completed a low-load knee extension exercise protocol consisting of 75 repetitions distributed across four sets: 30, 15, 15, and 15 repetitions. During this condition, a pressure cuff was placed on the proximal thigh and inflated to 80% of the participant's individualized arterial occlusion pressure. Surface electromyography of the vastus lateralis was recorded continuously during the protocol.
Low-load knee extension exercise without blood flow restriction
Participants completed the same low-load knee extension exercise protocol consisting of 75 repetitions distributed across four sets: 30, 15, 15, and 15 repetitions, without application of blood flow restriction. Surface electromyography of the vastus lateralis was recorded continuously during the protocol.
Locations (1)
University of Extremadura
Badajoz, Badajoz, Spain