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A Positron Emission Tomography Study to Assess the Occupancy of M4 Muscarinic Acetylcholine Receptors by BMS-986521 in Healthy Adult Participants
Sponsor: Bristol-Myers Squibb
Summary
The purpose of this study is to Assess the Occupancy of M4 Muscarinic Acetylcholine Receptors by BMS-986521 in Healthy Adult Participants
Official title: A Phase 1, Open-label, Positron Emission Tomography (PET) Imaging Study to Evaluate M4 Muscarinic Acetylcholine Receptor Occupancy in the Central Nervous System Using [11C]MK-6884 PET Tracer Before and After Oral Administration of Multiple Doses of BMS-986521 in Healthy Adult Participants
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2026-06-25
Completion Date
2026-12-27
Last Updated
2026-07-10
Healthy Volunteers
Yes
Conditions
Interventions
BMS-986521
Specified dose on specified days
Locations (1)
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg
Leuven, Belgium