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RECRUITING
NCT07655518
PHASE1

A Positron Emission Tomography Study to Assess the Occupancy of M4 Muscarinic Acetylcholine Receptors by BMS-986521 in Healthy Adult Participants

Sponsor: Bristol-Myers Squibb

View on ClinicalTrials.gov

Summary

The purpose of this study is to Assess the Occupancy of M4 Muscarinic Acetylcholine Receptors by BMS-986521 in Healthy Adult Participants

Official title: A Phase 1, Open-label, Positron Emission Tomography (PET) Imaging Study to Evaluate M4 Muscarinic Acetylcholine Receptor Occupancy in the Central Nervous System Using [11C]MK-6884 PET Tracer Before and After Oral Administration of Multiple Doses of BMS-986521 in Healthy Adult Participants

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

12

Start Date

2026-06-25

Completion Date

2026-12-27

Last Updated

2026-07-10

Healthy Volunteers

Yes

Interventions

DRUG

BMS-986521

Specified dose on specified days

Locations (1)

Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg

Leuven, Belgium