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COMPLETED
NCT07655739

The Effects of Sleeve Gastrectomy on Fractalkine

Sponsor: Mehmet Buğra Bozan

View on ClinicalTrials.gov

Summary

Fractalkine (CX3CL1) is a unique chemokine involved in leukocyte adhesion, migration, and obesity-associated adipose tissue inflammation. Although bariatric surgery results in substantial weight loss and metabolic improvement, the temporal pattern of circulating CX3CL1 levels following laparoscopic sleeve gastrectomy (LSG) remains poorly understood. This study aimed to evaluate longitudinal changes in serum CX3CL1 levels after LSG and to investigate their association with postoperative weight loss.

Official title: Temporal Changes in Fractalkine (CX3CL1) Levels Following Sleeve Gastrectomy and Their Association With Weight Loss: A Prospective Study

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

40

Start Date

2025-09-04

Completion Date

2026-02-04

Last Updated

2026-06-18

Healthy Volunteers

No

Locations (1)

Elazig Fethi Sekin City Hospital

Elâzığ, Turkey (Türkiye)