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High-density Flexible ECoG for Epilepsy Surgery - A Single-Arm ECT
Sponsor: Beijing Tiantan Hospital
Summary
What's the clinical value of high-density flexible electrocorticography (ECoG) for guiding the resection of epileptogenic zone (EZ) in epilepsy surgery?
Official title: Precision Resection of the Epileptogenic Zone Using Intraoperative Subdural High-density Flexible Electrocorticography - A Single-Arm Trial With an External Historical Control Cohort
Key Details
Gender
All
Age Range
3 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
85
Start Date
2026-07-01
Completion Date
2028-12-31
Last Updated
2026-06-18
Healthy Volunteers
No
Conditions
Interventions
High-density Flexible Electrocorticography
During resective epilepsy surgery, a sterile high-density flexible electrocorticography will be placed on the exposed cortical surface over the suspected epileptogenic zone and adjacent cortex. The array will be used for high-spatial-resolution intraoperative ECoG recording and real-time analysis of epileptiform activity, including interictal spikes, high-frequency oscillations, spatial discharge gradients, and propagation patterns. The intraoperative ECoG findings will be provided to the surgical team to assist in defining the epileptogenic zone and tailoring the extent of resection. The high-density ECoG is used for intraoperative recording only and will be removed before wound closure.
Locations (1)
Beijing Tiantan Hospital
Beijing, Beijing Municipality, China