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Daily Versus Alternate-Day Oral Iron Therapy for Anemia in Second-Trimester Pregnancy
Sponsor: Pakistan Air Force (PAF) Hospital Islamabad
Summary
This randomized controlled trial compares daily versus alternate-day oral iron supplementation in pregnant women with iron deficiency anemia during the second trimester. The study evaluates changes in hemoglobin and serum ferritin, treatment adherence, and gastrointestinal side effects to inform more patient-centered, physiologically aligned dosing strategies.
Official title: Daily Versus Alternate-Day Oral Iron Therapy for Anemia Correction in Second-Trimester Pregnant Patients: A Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
184
Start Date
2026-09
Completion Date
2027-02
Last Updated
2026-06-18
Healthy Volunteers
No
Interventions
Ferrous Sulfate
Oral ferrous sulfate 325 mg tablets (approximately 65 mg elemental iron per tablet) administered for four weeks according to the assigned dosing schedule. All participants receive standardized counseling on administration, diet, side effects, and adherence, and are issued a dose diary.
Locations (1)
Pakistan Air Force (PAF) Hospital Islamabad
Islamabad, Pakistan