Clinical Research Directory

Olfactory Transcranial Focused Ultrasound

Sponsor: Medical University of South Carolina

Summary

This study investigates the causal effects of low-intensity transcranial focused ultrasound (tFUS) on odor valence perception and odor-elicited avoidance behaviors in healthy adults. Participants undergo sham and active tFUS targeting the amygdala (AMYG) and ventral striatal olfactory tubercle (VSOT) in a within-subject, randomized, sham-controlled crossover design. Outcomes include subjective odor ratings and objective neurophysiological and behavioral indices of odor valence processing. This research is exploratory and mechanistic in nature and is not intended to evaluate clinical safety or therapeutic efficacy.

Official title: Modulation of Olfactory Valence by Transcranial Focused Ultrasound (tFUS)

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Locations (1)