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NOT YET RECRUITING
NCT07658482
PHASE1

A Phase 1 Study to Evaluate Pharmacokinetics, Safety and Tolerability of ZL-1503 in Healthy Volunteers

Sponsor: Zai Lab (Shanghai) Co., Ltd.

View on ClinicalTrials.gov

Summary

This is a phase 1, single dose, randomized, open-label, parallel-group study to evaluate the pharmacokinetics (PK), safety, tolerability and immunogenicity of ZL-1503 and to explore its PD biomarkers following a single subcutaneous (SC) or intravenous (IV) administration in healthy volunteers.

Official title: A Phase 1, Randomized, Open-label, Parallel-group Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ZL-1503 Following a Single Dose of Subcutaneous or Intravenous Administration in Healthy Volunteers.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

36

Start Date

2026-09-03

Completion Date

2027-11-10

Last Updated

2026-08-20

Healthy Volunteers

Yes

Interventions

DRUG

ZL-1503

Healthy volunteers will receive a single intravenous dose of ZL-1503.

DRUG

ZL-1503

Healthy volunteers will receive a single subcutaneous administration at Dose 1.

DRUG

ZL-1503

Healthy volunteers will receive a single subcutaneous administration at Dose 2.

Locations (1)

Momentum Auckland

Takapuna, Auckland, New Zealand