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Implementation of Vancomycin Powder Application in the Emergency Department for Open Fractures
Sponsor: Atlantic Health System
Summary
To evaluate the feasibility, safety, and potential efficacy of applying vancomycin powder locally to open fractures in the emergency department prior to definitive surgical intervention.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-06-10
Completion Date
2027-06-10
Last Updated
2026-06-22
Healthy Volunteers
No
Conditions
Interventions
Vancomycin (VAN) treatment
A single 1-gram dose of sterile vancomycin powder is applied directly to the open fracture wound in the Emergency Department after initial wound assessment and irrigation and prior to definitive operative debridement and fixation.
Standard Open Fracture Care
Standard management of open fractures according to institutional protocols, including intravenous antibiotics, wound care, irrigation, operative debridement, and fracture stabilization as indicated, without topical vancomycin powder application in the Emergency Department.
Locations (1)
Morristown Medical Center
Morristown, New Jersey, United States