Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis
Sponsor: Khyber Medical University Peshawar
Summary
OA is a degenerative bone disease more common in postmenopausal women. Diabetes and obesity are common risk factors for the development of OA. The common symptoms include pain and disability of the affected joint, leading to mobility issues. Acetyl L-carnitine due to its known anti-inflammatory, chondroprotective, and improved insulin-sensitizing effects may help in alleviating the symptoms and progression of OA in obese diabetic postmenopausal women.
Official title: Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis: Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
55 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-11-01
Completion Date
2026-08-30
Last Updated
2026-06-22
Healthy Volunteers
Yes
Conditions
Interventions
Acetyl-l-carnitine
Acetyl L-Carnitine capsules, 1.5 g administered orally twice daily (total daily dose 3 g) after meals for 12 weeks in addition to conventional osteoarthritis treatment.
Placebo
Matching placebo capsules administered orally twice daily for 12 weeks in addition to conventional osteoarthritis treatment.
Locations (1)
Khalifa Gulnawaz Teaching Hospital, DHQ Teaching Hospital
Bannu, KPK, Pakistan