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Bacillus Clausii Versus Multistrain Probiotics for Acute Watery Diarrhea in Children
Sponsor: Children Hospital and Institute of Child Health, Lahore
Summary
This randomized controlled trial will compare Bacillus clausii (Enterogermina) and a multistrain probiotic preparation (Ecotec) in children aged 1-5 years with acute watery diarrhea. Participants will receive one of the probiotic treatments along with standard therapy including oral rehydration solution and zinc supplementation. The study will evaluate the duration of diarrhea, stool frequency, and stool consistency.
Official title: Comparison of Effectiveness of Bacillus Clausii and Multistrain Probiotics (Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Bifidobacterium, Streptococcus Thermophilus) in the Management of Children With Acute Watery Diarrhea: A Randomised Controlled Trial
Key Details
Gender
All
Age Range
1 Year - 5 Years
Study Type
INTERVENTIONAL
Enrollment
138
Start Date
2026-08
Completion Date
2026-11
Last Updated
2026-06-24
Healthy Volunteers
No
Conditions
Interventions
Enterogermina
Bacillus clausii oral suspension containing 2 billion spores administered once daily for 5 days.
Ecotec
Multistrain probiotic preparation containing Lactobacillus acidophilus, Lactobacillus bulgaricus, Bifidobacterium species, and Streptococcus thermophilus administered once daily for 5 days.
Locations (1)
Children Hospital and Institute of Child Health, Lahore
Lahore, Punjab Province, Pakistan