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NOT YET RECRUITING
NCT07660367
NA

Bacillus Clausii Versus Multistrain Probiotics for Acute Watery Diarrhea in Children

Sponsor: Children Hospital and Institute of Child Health, Lahore

View on ClinicalTrials.gov

Summary

This randomized controlled trial will compare Bacillus clausii (Enterogermina) and a multistrain probiotic preparation (Ecotec) in children aged 1-5 years with acute watery diarrhea. Participants will receive one of the probiotic treatments along with standard therapy including oral rehydration solution and zinc supplementation. The study will evaluate the duration of diarrhea, stool frequency, and stool consistency.

Official title: Comparison of Effectiveness of Bacillus Clausii and Multistrain Probiotics (Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Bifidobacterium, Streptococcus Thermophilus) in the Management of Children With Acute Watery Diarrhea: A Randomised Controlled Trial

Key Details

Gender

All

Age Range

1 Year - 5 Years

Study Type

INTERVENTIONAL

Enrollment

138

Start Date

2026-08

Completion Date

2026-11

Last Updated

2026-06-24

Healthy Volunteers

No

Interventions

DRUG

Enterogermina

Bacillus clausii oral suspension containing 2 billion spores administered once daily for 5 days.

DRUG

Ecotec

Multistrain probiotic preparation containing Lactobacillus acidophilus, Lactobacillus bulgaricus, Bifidobacterium species, and Streptococcus thermophilus administered once daily for 5 days.

Locations (1)

Children Hospital and Institute of Child Health, Lahore

Lahore, Punjab Province, Pakistan