Clinical Research Directory

Inclusion Criteria: * Men aged 50 yars or older ; * Postmenopausal women ; * Afilliated with a health insurance and system ; * Written informed consent obtained. * Group 1 : Clincal osteoporotic vertebral fracture confirmed by imaging within the previous month ; Followed in the Rheumatology department for management of vertebral fracture. * Group 2 : Densitometric osteoporosis (T-score ≤ -2.5) ; No history of severe osteoporotic fracture ; No history of clinical or morphometric vertebral fracture. Exclusion Criteria: * Legal protection measure (guardianship, curatorship); * inability to provide informed consent ; * refusal to participate ; * Vertebral fracture related to tumor, * infection, trauma or non osteoporotic causes ; * asymptomatic vertebral fracture discovered incidentally ; * Severe densitometric osteoporosis for group 2 ; * Previous severe osteoporotic fracture for group B.