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To Study the Efficacy and Safety of Doxercalciferol on Spinal and Femoral Density in Postmenopausal Osteopenic Women in a Long Term 2 Year Study
Sponsor: Creighton University
Summary
A clinical trial to compare the effect of doxercalciferol or placebo in preventing bone loss from the spine and femur in postmenopausal women
Official title: Efficacy and Safety of Doxercalciferol on Spinal and Femoral Density in Postmenopausal Osteopenic Women
Key Details
Gender
FEMALE
Age Range
60 Years - 78 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
1989-11-14
Completion Date
1994-12-23
Last Updated
2026-06-22
Healthy Volunteers
No
Conditions
Interventions
doxercalciferol capsules, Hectorol®
doxercalciferol capsules given in escalating doses from 1mcg to 5mcg daily.If serum calcium is elevated at any dose then that dose is maintained long term for 24 months.The change in bone mineral density will be measured at baseline ,12 and 24 months
Matched Placebo (Capsules)
oral doses increased from 1 to 5mcg once daily until serum calcium is elevated and given for 2 years.The change in bone mineral density will be measured at baseline ,12 and 24 months
Locations (1)
Creighton University Medical center
Omaha, Nebraska, United States