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NOT YET RECRUITING
NCT07660588
NA

Brief Bronchial Suction for Lung Collapse During Uniportal VATS

Sponsor: Mahidol University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn whether a brief suction of the airway going to the surgical lung (bronchus) can help the lung collapse faster and more completely during uniportal video-assisted thoracoscopic surgery (UVATS). This type of surgery is performed through a small incision in the chest, and good lung collapse helps the surgeon see and work safely. The main questions it aims to answer are 1. Does brief bronchial suction improve the quality of lung collapse 1 minute after chest cavity is opened? 2. Does brief bronchial suction help reach satisfactory lung collapse faster? Researchers will compare patients who receive brief bronchial suction and those who do not. This is to see if suction improves and fastens lung collapse, reduce the need for additional steps if lung is not adequately collapsed, affect inflammation, oxygenation, postoperative pulmonary complications, operative time, and the duration of one-lung ventilation. Participants will 1. Undergo UVATS under general anesthesia 2. Have a double-lumen breathing tube placed as part of the standard anesthetic care 3. Be randomly assigned to either receive bronchial suction for one minute or receive no bronchial suction 4. Have the surgical team assess the quality of lung collapse at different time points 5. Have information collected from the routine anesthesia and surgical records such as oxygen levels during surgery, length of surgery and lung-related complications within 7 days after surgery

Official title: Effect of Brief Bronchial Suction on the Quality of Non-Ventilated Lung Collapse and Time to Adequate Surgical Exposure During Uniportal Video-Assisted Thoracoscopic Surgery: a Randomized Patient- and Surgeon-Blinded Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-11

Completion Date

2028-07

Last Updated

2026-10-07

Healthy Volunteers

Yes

Interventions

OTHER

bronchial suction

Participants will receive bronchial suction at -30 cmH₂O through the bronchoscopy port of the operative lumen of the double-lumen endotracheal tube on two occasions: (1) during a 60-second apnea period immediately before initiation of one-lung ventilation and (2) during a 60-second apnea period immediately after pleural opening. Following the first suction period, the bronchoscopy port of the operative lumen will be closed. The bronchoscopy port of the operative lumen will be opened to ambient air following the second suction period after pleural entry.

OTHER

Sham Control

Participants will undergo the same 60-second apnea periods as the bronchial suction group immediately before initiation of one-lung ventilation and immediately after pleural opening. The suction device will be activated for 60 seconds to produce sham suction noise but will not be connected to the patient.

Locations (1)

Siriraj Hospital, Mahidol University

Bangkok, Thailand