Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effect of Minimally Invasive Extracorporeal Circulation on Optic Nerve Sheath Diameter and Stroke Incidence in Isolated Open Heart Surgery
Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital
Summary
This prospective randomized controlled trial compares the effects of Minimally Invasive Extracorporeal Circulation (MiECC) versus conventional cardiopulmonary bypass (CPB) on optic nerve sheath diameter (ONSD) and postoperative stroke incidence in adult patients undergoing isolated open heart surgery. ONSD will be measured by ultrasound at 7 predefined time points (T0-T6). Primary outcomes include perioperative ONSD changes and 30-day stroke incidence. Secondary outcomes include TIA, delirium (CAM-ICU), MoCA scores, ICU and hospital stay, AKI, and transfusion requirements.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-11-01
Completion Date
2026-09-01
Last Updated
2026-06-22
Healthy Volunteers
No
Locations (1)
University of Health Sciences Bursa Yüksek Ihtisas Training and Research Hospital
Bursa, Yıldırım, Turkey (Türkiye)