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DEPART Study at Yale
Sponsor: Yale University
Summary
This is a randomized study to determine whether radiation therapy reduces the risk of progression / recurrence of Dupuytren's disease / contracture.
Official title: Dupuytren's Disease Evaluation of Preventative or Adjuvant Radiation Therapy: DEPART
Key Details
Gender
All
Age Range
30 Years - Any
Study Type
INTERVENTIONAL
Enrollment
158
Start Date
2026-08-01
Completion Date
2028-12-30
Last Updated
2026-06-22
Healthy Volunteers
No
Conditions
Interventions
Radiation Therapy
Radiation therapy (RT) should commence within 12 weeks of randomization in the prevention group and within 12 weeks of local treatment (NA) for the adjuvant group. RT will consist of 30Gy in 10 equal fractions. The RT schedule will be 5 initial fractions, then a 4-12 week break and then the final 5 fractions. Each group of 5 treatments must be delivered within a 7 day period.
Locations (1)
Greenwich Hospital
Greenwich, Connecticut, United States