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Intravenous Lidocaine to Prevent Post-Fundal Pressure Headache During Cesarean Section
Sponsor: Tanta University
Summary
This prospective randomized controlled multicenter study will be conducted to evaluate the effects of pre-emptive IV lidocaine dose on the incidence and severity of intraoperative headache that may occur after the extra-abdominal manual uterine fundal pressure in patients undergoing cesarean section under spinal anesthesia.
Official title: Pre-emptive Single Intravenous Lidocaine Dose to Prevent Post-Fundal Pressure Headache During Cesarean Section: The LID-HEAD Multi-center Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
680
Start Date
2026-07-01
Completion Date
2026-11-02
Last Updated
2026-07-06
Healthy Volunteers
No
Interventions
Lidocaine IV
IV lidocaine 1.5 mg/kg (diluted with 0.9% isotonic saline to a total volume of 10 ml) over 5 minutes with the start of skin incision after ensuring negative baseline headache.
Saline 0.9%
IV 10 ml isotonic saline over 5 minutes with the start of skin incision after ensuring negative baseline headache.
Locations (1)
Tanta University Hospitals
Tanta, Gharbia Governorate, Egypt