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Breast-milk Enema Administration to Stimulate Passage of Meconium
Sponsor: Wake Forest University Health Sciences
Summary
Lack of passage of meconium in preterm infants delays feeding advancement and may represent a risk factor for necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP). Usual management of meconium impaction has included glycerin suppositories and normal saline enemas. Various methods are used in routine neonatal care to promote meconium evacuation; however, there is no consensus on the agents used and the frequency of applications
Official title: Breast-Milk Enema Administration to Stimulate Meconium Passage in Preterm Infants
Key Details
Gender
All
Age Range
23 Weeks - 28 Weeks
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-07
Completion Date
2027-01
Last Updated
2026-06-23
Healthy Volunteers
No
Conditions
Interventions
breast milk
A small-volume rectal enema consisting of 5 mL/kg of fresh mother's own breast milk will be administered as a single dose, with the option for one repeat dose at 24 hours if clinically indicated.
Locations (1)
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States