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NOT YET RECRUITING
NCT07664592
PHASE3

Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies

Sponsor: Colgate Palmolive

View on ClinicalTrials.gov

Summary

The purpose of this clinical study is to evaluate and compare how well three different types of toothpaste technologies work to relieve tooth sensitivity, also known as dentin hypersensitivity. The study asks the question: How effective are toothpastes containing 8% Arginine, 8% Arginine with Zinc Phosphate, or 5% Calcium Sodium Phosphosilicate (CSPS) at providing immediate and short-term relief for people suffering from sensitive teeth?

Official title: Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies on Instant and Short-term Relief of Dentin Hypersensitivity: a Randomized Clinical Trial

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

132

Start Date

2026-06-29

Completion Date

2026-09-30

Last Updated

2026-06-24

Healthy Volunteers

No

Interventions

DRUG

8% arginine + Zinc toothpaste

A commercially available fluoride toothpaste containing 8% arginine + Zinc Phosphate

DRUG

5% Calcium Sodium Phosphosilicate toothpaste

A commercially available fluoride toothpaste containing 5% Calcium Sodium Phosphosilicate (CSPS)

DRUG

8% arginine toothpaste

A commercially available fluoride toothpaste containing 8% arginine