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Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies
Sponsor: Colgate Palmolive
Summary
The purpose of this clinical study is to evaluate and compare how well three different types of toothpaste technologies work to relieve tooth sensitivity, also known as dentin hypersensitivity. The study asks the question: How effective are toothpastes containing 8% Arginine, 8% Arginine with Zinc Phosphate, or 5% Calcium Sodium Phosphosilicate (CSPS) at providing immediate and short-term relief for people suffering from sensitive teeth?
Official title: Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies on Instant and Short-term Relief of Dentin Hypersensitivity: a Randomized Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
132
Start Date
2026-06-29
Completion Date
2026-09
Last Updated
2026-08-07
Healthy Volunteers
No
Interventions
8% arginine + Zinc toothpaste
A commercially available fluoride toothpaste containing 8% arginine + Zinc Phosphate
5% Calcium Sodium Phosphosilicate toothpaste
A commercially available fluoride toothpaste containing 5% Calcium Sodium Phosphosilicate (CSPS)
8% arginine toothpaste
A commercially available fluoride toothpaste containing 8% arginine
Locations (1)
IEAPOM
Porto Alegre, Rio Grande do Sul, Brazil