Clinical Research Directory

Inclusion Criteria: 1. Adult subjects of either gender aged more than 18 years. 2. Body Mass index (BMI) between ≥25 and ≤39.9 kg/m2. 3. Duration (in days) of COVID-19 symptoms prior to randomization is a \> 2 days and ≤ 10 days of COVID-19 symptoms. 4. Two (2) positive (rapid) antigen diagnostic tests for SARS-CoV-2 (tests listed under FDA EUA) and administered within 2 hours of each other. Enrolled subjects will undergo subsequent molecular standard reverse transcriptase polymerase chain reaction (rt-PCR) assay. Enrolled subjects with a negative PCR test will be replaced by other individuals.) 5. Subjects with a minimal baseline severity score for COVID-19-related symptoms defined as at least two symptoms with a score of 2 or higer, using normalized grading scale. 6. Female subjects of non-childbearing potential (e.g., non fertile, pre-menarche, permanently sterile \[e.g., underwent hysterectomy, bilateral salpingectomy or bilateral ovariectomy\] or post-menopausal \[history of no menses for at least 12 months without an alternative medical cause\] or Woman of childbearing potential\* with a negative serum or urine pregnancy test Exclusion Criteria: 1. Subjects who test positive for SARS-CoV-2 using a virologic test but have no symptoms consistent with COVID-19. (Asymptomatic or presymptomatic infection). 2. Subjects who have SpO2 \<94% on room air at sea level (Severe illness). 3. Subjects who have respiratory failure (Critical illness). 4. Subjects who have septic shock (Critical illness). 5. Subjects who have multiple organ dysfunction (Critical illness). 6. Subjects presenting with an underlying medical condition or risk factor that conclusively disposes that subject to a higher risk for progression to severe COVID-19, as per the CDC's Systematic Review Process. 7. Subjects hospitalized within the previous 15 days. 8. Subjects discharged from the Emergency Room within the previous 15 days. 9. Subjects not expected to survive for three (3) months due to other pre-existing medical conditions such as end-stage neoplasm or other diseases. 10. Less than 18 years.