Clinical Research Directory

Inclusion Criteria: * Able to comprehend and are willing to sign the ICF and willing to follow the study procedures * Female, aged 18 years of age or older at the time of informed consent. * Histologically confirmed diagnosis of epithelial ovarian, fallopian tube, or primary peritoneal carcinoma of high-grade serous histology or other high-grade predominantly serous subtypes * The FIGO 2014 stage III or IV disease at initial diagnosis. * Underwent optimal PDS or IDS with residual disease ≤1 cm (R0 or R1 resection) * Completed first-line platinum-based chemotherapy (minimum 4 cycles of carboplatin and paclitaxel, or equivalent, received in either neoadjuvant or adjuvant, or both settings). * In the presence of measurable target lesion, achieved CR or PR per investigator assessment based on RECIST 1.1 after completion of chemotherapy. In the absence of measurable target lesion, no new lesion or overt progression per investigator assessment based on RECIST 1.1 after completion of chemotherapy. * A minimum of 4 weeks from screening since the last dose of first-line platinum-based chemotherapy but not more than 12 weeks from screening since the last dose of first-line platinum-based chemotherapy. * No evidence of radiologic or clinical progression between the end of chemotherapy and baseline screening. * Known BRCAwt status. * HRP confirmed * No prior, current, or planned treatment with bevacizumab or PARPi in the first-line maintenance setting. * ECOG performance status of 0 or 1. * Adequate haematologic and organ function * Negative pregnancy test for WOCBP. * HLA type matching Cryptivax-1001 Exclusion Criteria: * Non-epithelial or low malignant potential ovarian tumours * Presence of uncontrolled ascites or pleural effusion requiring drainage within 4 weeks of screening. * Concurrent malignancy or history of another malignancy within the past 3 years except for malignancies with a negligible risk of metastasis or death * Active autoimmune disease requiring systemic immunosuppression * Uncontrolled intercurrent illness that, in the opinion of the investigator, would compromise participant safety or interfere with study assessments * History of anaphylactic reaction to mRNA-LNP therapies. * Previous treatment with any cancer vaccine, checkpoint inhibitor, or adoptive cellular immunotherapy. * Administration of any vaccine within 30 days prior to first dosing. * Participation in a clinical study involving administration of an IMP (new chemical entity) in the past 90 days or 5 half-lives of that drug (if known) prior to first dosing, whichever is longer.