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NOT YET RECRUITING
NCT07665606

JUgular Gating for Upright Level Adjustment and Targeted Enhancement of Cerebral Perfusion

Sponsor: University Hospital, Bordeaux

View on ClinicalTrials.gov

Summary

Investigators aim to demonstrate that the evolution of intracranial pressure (ICP) is nonlinear and may be influenced by jugular vein collapse. This collapse is estimated to occur at the angle where the hydrostatic pressure of the blood column matches the central venous pressure, and it can be assessed using ultrasonography. This approach allows for the determination of an individualized tilt angle, optimizing cerebral perfusion pressure without compromising venous drainage.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

30

Start Date

2026-09-01

Completion Date

2027-03-31

Last Updated

2026-06-24

Healthy Volunteers

No

Interventions

PROCEDURE

Ultrasound assessment

After the routine nursing care, during patient repositioning to 30 ° assessments are performed at 0, 10° 20° 30°, and at a calculated threshold angle α. At each angle intracranial pressure , cerebral perfusion pressure and ultrasound assessment of cerebral blood flow velocities and internal jugular vein cross-sectional area at three cervical levels are recorded.

Locations (1)

Bordeaux university hospital

Bordeaux, France