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AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight
Sponsor: Novo Nordisk A/S
Summary
The purpose of this clinical study is to find out if zenagamtide is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get zenagamtide (the treatment being tested) or placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.
Official title: Efficacy and Safety of Zenagamtide s.c. Once-weekly in Asian Participants With Overweight or Obesity (AMAZE 13)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2027-01-07
Completion Date
2029-01-11
Last Updated
2026-06-25
Healthy Volunteers
No
Conditions
Interventions
Zenagamtide
Zenagamtide will be administered subcutaneously using PDS290 pre-filled pen-injectors to one of the body parts: thigh, abdomen or upper arm.
Placebo ( matched to Zenagamtide)
Placebo matched to Zenagamtide will be administered subcutaneously using PDS290 pre-filled pen-injectors to one of the body parts: thigh, abdomen or upper arm.
Locations (11)
Nirmal Hospital Pvt. Ltd.
Surat, Gujarat, India
SSG Hospital, Baroda
Vadodara, Gujarat, India
Shree Mahalaxmi DIATONE Institute
Kohlapur, Maharashtra, India
Excel Endocrine Centre
Kolhāpur, Maharashtra, India
Maulana Azad Medical College
Delhi, New Delhi, India
Diabetes Research Center, Hyderabad
Hyderabad, Telangana, India
SMS Hospital
Jaipur, India
OCROM Clinic_Internal medicine
Suita-shi, Osaka, Japan
Tokyo-Eki Center-building Clinic_Internal Medicine
Tokyo, Japan
Fukuwa Clinic_Internal Medicine
Tokyo, Japan
ToCROM Clinic_Internal Medicine
Tokyo, Japan