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Anti-inflammation Treatment for Idiopathic Inflammatory Myopathies
Sponsor: Chinese University of Hong Kong
Summary
The goal of this clinical trial is to learn if the drug Maraviroc works to treat refractory idiopathic inflammatory myopathy (myositis) in patients who have not responded well to traditional therapies. It will also learn about how the drug affects muscle inflammation and function. The main questions it aims to answer are: Does Maraviroc reduce inflammation in the muscles? Does Maraviroc improve patients' muscle function and overall clinical symptoms? This is an open-label study, meaning researchers will give Maraviroc to all participants (there is no placebo) to see if the drug works to treat refractory myositis. Participants will: Take a 300mg Maraviroc tablet every day for 12 weeks Undergo exams and tests with their doctors to check their muscle function, symptom improvement, and specific health markers (like enzyme levels)
Official title: A Novel Anti-inflammation Treatment for Idiopathic Inflammatory Myopathies
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2026-09-01
Completion Date
2029-08-31
Last Updated
2026-06-25
Healthy Volunteers
No
Conditions
Interventions
maraviroc (Selzentry, Celsentri)
The first study of repurposing Maraviroc for the treatment of myositis
Locations (1)
Prince of Wales hospital
Hong Kong, Hong Kong