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NOT YET RECRUITING
NCT07668505
PHASE4

Anti-inflammation Treatment for Idiopathic Inflammatory Myopathies

Sponsor: Chinese University of Hong Kong

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if the drug Maraviroc works to treat refractory idiopathic inflammatory myopathy (myositis) in patients who have not responded well to traditional therapies. It will also learn about how the drug affects muscle inflammation and function. The main questions it aims to answer are: Does Maraviroc reduce inflammation in the muscles? Does Maraviroc improve patients' muscle function and overall clinical symptoms? This is an open-label study, meaning researchers will give Maraviroc to all participants (there is no placebo) to see if the drug works to treat refractory myositis. Participants will: Take a 300mg Maraviroc tablet every day for 12 weeks Undergo exams and tests with their doctors to check their muscle function, symptom improvement, and specific health markers (like enzyme levels)

Official title: A Novel Anti-inflammation Treatment for Idiopathic Inflammatory Myopathies

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2026-09-01

Completion Date

2029-08-31

Last Updated

2026-06-25

Healthy Volunteers

No

Conditions

Interventions

DRUG

maraviroc (Selzentry, Celsentri)

The first study of repurposing Maraviroc for the treatment of myositis

Locations (1)

Prince of Wales hospital

Hong Kong, Hong Kong