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Cannabis Effects on Opioid Self-Administration
Sponsor: Shanna Babalonis, PhD
Summary
The study will enroll participants with opioid use disorder and participants will reside at the University of Kentucky Hospital for this 6-week inpatient trial. During this time, double-blind doses of cannabis and opioids will be administered. The goal of the project is to determine if cannabis can alter the drive/desire to take opioids.
Official title: Impact of Cannabis on Opioid Self-Administration
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-07-30
Completion Date
2031-07-30
Last Updated
2026-06-25
Healthy Volunteers
No
Conditions
Interventions
Cannabis
Cannabis is administered three times daily during the active cannabis treatment period.
Placebo Cannabis
Matched placebo cannabis is administered three times daily during the placebo treatment period.
Intranasal Opioid Agonist
Intranasal opioid agonists are administered during sample and self-administration sessions
Oral Opioid Agonist
Oral opioid agonist maintenance doses are administered four times daily throughout study participation.
Locations (1)
University of Kentucky Center on Drug and Alcohol Research
Lexington, Kentucky, United States