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Impact of E-Cigarette Smoking on Healing Response to Non-Surgical Periodontal Therapy
Sponsor: Ain Shams University
Summary
the goal of this clinical trial is to compare the effect of vaping vs traditional smoking on non surgical periodontal therapy . the main question it aims to answer is what is the impact of traditional smoking and vaping on periodontal health and how do IL-1B and IL-20 serve as mediators in the inflammatory processes linked to periodontal disease?
Official title: Impact of E-Cigarette Smoking on Healing Response to Non-Surgical Periodontal Therapy in the Management of Stage II Periodontitis (A Randomized Controlled Clinical Study With Biochemical Assessment )
Key Details
Gender
All
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
117
Start Date
2025-10-13
Completion Date
2026-03-04
Last Updated
2026-06-25
Healthy Volunteers
No
Conditions
Interventions
non surgical periodontal therapy
participants in all groups will recieve non surgical periodontal therapy including scaling and root planning performed using ultrasonic and hand instruments at baseline. oral hygiene instructions will be provided. periodontal parameters and GCF samples will be collected at baseline and follow up visit.
Locations (1)
faculty of dentistry , Ain shams university
Cairo, Cairo Governorate, Egypt