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Comparative Evaluation of Letrozole, L-Carnitine, and Combination Therapy on Sperm Quality and ART Outcomes in Idiopathic Oligoasthenoteratozoospermia: A Three-Arm Randomized Trial
Sponsor: Tehran University of Medical Sciences
Summary
This is a randomized clinical trial evaluating the efficacy of Letrozole, L-Carnitine, and their combination on sperm quality, oxidative stress, and ART outcomes in men with idiopathic oligoasthenoteratozoospermia.
Official title: Comparative Evaluation of the Efficacy of Letrozole, L-Carnitine, and Their Combination on Sperm Quality, Oxidative Stress, and ART Outcomes in Men With Idiopathic Oligoasthenoteratozoospermia: A Three-Arm Randomized Clinical Trial.
Key Details
Gender
MALE
Age Range
20 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2023-12-01
Completion Date
2026-03-31
Last Updated
2026-06-25
Healthy Volunteers
No
Interventions
Letrozole 2.5mg
Letrozole 2.5 mg tablet administered orally once daily for 3 months.
L-carnitine
L-Carnitine 1000 mg capsule administered orally once daily for 3 months.
Locations (1)
Shariati Hospital, Tehran University of Medical Sciences
Tehran, Iran