Clinical Research Directory

Inclusion Criteria: * internal fixation after fracture * presence of fistula and/or sinus tract or purulent drainage with dehiscence at the incision site * at least 2 positive deep tissue cultures or at least 3 positive soft tissue cultures * early onset of symptoms (6 weeks) * DAIR or implant removal/replacement due to fracture-related infection Exclusion Criteria: * Under 18 years old patients * prosthetic joint infection * only conservative treatment applied * pathological fracture due to primary bone tumor * simultaneous infection foci in the same extremity * fracture-related infection not confirmed by international consensus criteria * poor reduction after internal fixation * inappropriate or inadequate internal fixation * radiological images less than 1 year old * findings starting late (after 6 weeks)