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COMPLETED
NCT07669818
PHASE4

Efficacy of Dissolvable Mineral Loaded Starch Particles Strips in Providing Rapid Relief of Dentin Hypersensitivity: A Randomized Clinical Trial

Sponsor: Cairo University

View on ClinicalTrials.gov

Summary

Dentinal Hypersensitivity is a common condition associated with exposed root surfaces that causes short, sharp pain in response to thermal, evaporative, or tactile stimuli, negatively affecting patients' daily activities and oral hygiene practices. Current treatment approaches mainly focus on occluding dentinal tubules to reduce sensitivity. NovaMin-based toothpaste is widely used because of its ability to promote mineral deposition and dentinal tubule occlusion. Recently, dissolvable mineral-loaded starch particle strips have been introduced as a novel delivery system that may enhance mineral contact with exposed dentin and improve patient compliance. However, limited evidence exists regarding their clinical effectiveness compared with established desensitizing toothpastes. Therefore, this study is significant because it aims to evaluate whether these dissolvable strips can provide a comparable therapeutic effect to NovaMin-based toothpaste in managing dentinal hypersensitivity.

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

82

Start Date

2026-03-10

Completion Date

2026-05-20

Last Updated

2026-06-25

Healthy Volunteers

No

Interventions

OTHER

dissolvable mineral-loaded starch particle strips

dissolvable strips containing mineral-loaded starch particles applied according to the study protocol for the management of dentin hypersensitivity.

OTHER

Novamin containing toothpaste

Toothpaste containing calcium sodium phosphosilicate (NovaMin) used twice daily for the management of dentin hypersensitivity.

Locations (1)

King Salman International University

Cairo, Other, Egypt