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NOT YET RECRUITING
NCT07671092
EARLY_PHASE1

Imaging Study of a TROP2 Binder in Metastatic UC, HR+ and HER2- Breast Cancer, TNBC, and NSCLC

Sponsor: RayzeBio, Inc.

View on ClinicalTrials.gov

Summary

This imaging study aims to assess the feasibility, biodistribution, and dosimetry of a TROP2 binder in subjects with metastatic UC, HR+ and HER2- breast cancer, TNBC, or NSCLC.

Official title: A Phase 0 Imaging Study to Assess the Feasibility, Biodistribution, and Dosimetry of a Trophoblast Cell Surface Antigen 2 (TROP2) Binder in Metastatic Urothelial Cancer (UC), Hormone Receptor-Positive (HR+) and Human Epidermal Growth Factor Receptor 2-Negative (HER2-) Breast Cancer, Triple-Negative Breast Cancer (TNBC), and Non-Small-Cell Lung Cancer (NSCLC)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2026-06

Completion Date

2027-10

Last Updated

2026-06-26

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

RYZ211/212

Imaging Agent

Locations (1)

Research Facility

Christchurch, New Zealand