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Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine Extended-Release (NAL ER) Tablets
Sponsor: Trevi Therapeutics
Summary
The primary purpose is to evaluate the safety and efficacy of NAL ER for the treatment of chronic cough in participants with Idiopathic Pulmonary Fibrosis (IPF).
Official title: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Nalbuphine Extended-Release Tablets for the Treatment of Chronic Cough in Participants With Idiopathic Pulmonary Fibrosis
Key Details
Gender
All
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
306
Start Date
2026-06-29
Completion Date
2028-07
Last Updated
2026-07-10
Healthy Volunteers
No
Conditions
Interventions
NAL ER
Oral tablets
Placebo
Oral tablets
Locations (5)
Pulmonary Specialists of The Palm Beaches
Loxahatchee Groves, Florida, United States
Clinical Research and Associates, Inc.
Miami, Florida, United States
Clinical Research of Gastonia (CRG)
Gastonia, North Carolina, United States
El Paso Pulmonary Association, PA
El Paso, Texas, United States
Elevate Clinical Research
Houston, Texas, United States