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Ultrasound-Guided Hook-Wire Localization for Excision of Non-palpable Cervical Lesions Suspicious for Metastasis
Sponsor: Rusana Bark
Summary
The goal of this randomized controlled trial is to determine whether ultrasound-guided hook-wire localization improves surgical efficiency and accuracy compared with ultrasound-guided surgery alone for the excision of non-palpable or difficult-to-palpate cervical lesions suspicious for metastatic disease in adult patients. The main questions it aims to answer are: * Does ultrasound-guided hook-wire localization reduce operative time compared with ultrasound-guided excision alone? * Does hook-wire localization improve surgical precision, including successful retrieval of the target lesion for histopathological assessment? * Does hook-wire localization affect incision length, procedural difficulty, or the risk of surgical complications? Researchers will compare patients undergoing ultrasound-guided hook-wire localization followed by surgical excision with patients undergoing ultrasound-guided excision alone to determine whether hook-wire guidance improves surgical outcomes. Participants will: * Undergo ultrasound-guided localization and surgical excision of a cervical lesion or lymph node suspicious for malignancy. * Be randomly assigned to either: ultrasound-guided hook-wire localization before surgery, or ultrasound-guided excision without hook-wire localization. * Have surgical outcomes assessed, including operative time, incision length, successful lesion retrieval, procedural difficulty, and intraoperative or postoperative complications.
Official title: Open Lymph Node Biopsy in the Diagnostic Evaluation of Lymphoma and Non-palpable Cervical Cystic Lesions: a Clinical Study.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2021-04-15
Completion Date
2026-06-09
Last Updated
2026-06-29
Healthy Volunteers
No
Interventions
Ultrasound-guided hook-wire localization
Preoperative ultrasound-guided placement of a hook-wire into or adjacent to a non-palpable or difficult-to-palpate cervical lesion to facilitate intraoperative identification and surgical excision of the target lesion.
Ultrasound-guided surgical excision alone
Surgical excision of the target cervical lesion using ultrasound guidance for intraoperative identification, without preoperative hook-wire localization.
Locations (1)
Karolinska University Hospital
Stockholm, Stockholm County, Sweden