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COMPLETED
NCT07672912
NA

Ultrasound-Guided Hook-Wire Localization for Excision of Non-palpable Cervical Lesions Suspicious for Metastasis

Sponsor: Rusana Bark

View on ClinicalTrials.gov

Summary

The goal of this randomized controlled trial is to determine whether ultrasound-guided hook-wire localization improves surgical efficiency and accuracy compared with ultrasound-guided surgery alone for the excision of non-palpable or difficult-to-palpate cervical lesions suspicious for metastatic disease in adult patients. The main questions it aims to answer are: * Does ultrasound-guided hook-wire localization reduce operative time compared with ultrasound-guided excision alone? * Does hook-wire localization improve surgical precision, including successful retrieval of the target lesion for histopathological assessment? * Does hook-wire localization affect incision length, procedural difficulty, or the risk of surgical complications? Researchers will compare patients undergoing ultrasound-guided hook-wire localization followed by surgical excision with patients undergoing ultrasound-guided excision alone to determine whether hook-wire guidance improves surgical outcomes. Participants will: * Undergo ultrasound-guided localization and surgical excision of a cervical lesion or lymph node suspicious for malignancy. * Be randomly assigned to either: ultrasound-guided hook-wire localization before surgery, or ultrasound-guided excision without hook-wire localization. * Have surgical outcomes assessed, including operative time, incision length, successful lesion retrieval, procedural difficulty, and intraoperative or postoperative complications.

Official title: Open Lymph Node Biopsy in the Diagnostic Evaluation of Lymphoma and Non-palpable Cervical Cystic Lesions: a Clinical Study.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2021-04-15

Completion Date

2026-06-09

Last Updated

2026-06-29

Healthy Volunteers

No

Interventions

PROCEDURE

Ultrasound-guided hook-wire localization

Preoperative ultrasound-guided placement of a hook-wire into or adjacent to a non-palpable or difficult-to-palpate cervical lesion to facilitate intraoperative identification and surgical excision of the target lesion.

PROCEDURE

Ultrasound-guided surgical excision alone

Surgical excision of the target cervical lesion using ultrasound guidance for intraoperative identification, without preoperative hook-wire localization.

Locations (1)

Karolinska University Hospital

Stockholm, Stockholm County, Sweden