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COMPLETED
NCT07673003
PHASE4

Sevoflurane Versus Propofol for Laryngeal Mask Airway Placement in Children Undergoing Surgery

Sponsor: Children's Hospital and Institute of Child Health, Multan

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare two commonly used anesthetic medicines, sevoflurane and propofol, for inserting a laryngeal mask airway (LMA) in children undergoing minor elective surgery. A laryngeal mask airway is a device placed in the throat to help children breathe safely during anesthesia. The main questions this study aims to answer are: * Does sevoflurane produce a faster onset of anesthesia than propofol? * Is there a difference between sevoflurane and propofol in the time required to achieve jaw relaxation for LMA insertion? * Is there a difference between the two medicines in the time required for successful LMA insertion? The researchers hypothesize that children receiving sevoflurane will have a shorter induction time than those receiving propofol. A total of 170 children aged 4 to 12 years who are undergoing minor surgical procedures below the umbilicus will participate in the study. Participants will be randomly assigned to receive either intravenous propofol or inhaled sevoflurane for induction of anesthesia. During the procedure, the anesthesia team will measure the time taken to lose consciousness, the time required to achieve adequate jaw relaxation, and the time needed for successful insertion of the laryngeal mask airway. These measurements will help determine which anesthetic agent provides better conditions for LMA insertion in children.

Official title: Comparison of Sevoflurane and Propofol for Laryngeal Mask Airway Insertion in Children

Key Details

Gender

All

Age Range

4 Years - 12 Years

Study Type

INTERVENTIONAL

Enrollment

170

Start Date

2025-06-01

Completion Date

2025-11-30

Last Updated

2026-06-29

Healthy Volunteers

No

Interventions

DRUG

propofol

Intravenous propofol 3 mg/kg bolus will be administered for induction of general anesthesia before LMA insertion in pediatric patients.

DRUG

Sevoflurane

Sevoflurane 7% will be delivered via inhalation in a nitrous oxide/oxygen mixture (2:1) for induction of general anesthesia prior to LMA insertion in pediatric patients.

Locations (1)

Children's Hospital and Institute of Child Health Multan

Multan, Punjab Province, Pakistan