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NOT YET RECRUITING
NCT07673042
NA

Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal Endoscopy

Sponsor: General Hospital of Ningxia Medical University

View on ClinicalTrials.gov

Summary

To investigate the independent effects and interaction of pre-oxygenation position (left lateral vs left lateral with 30° head-up tilt) and examination position (left lateral vs left lateral with 30° head-up tilt) on hypoxemia during painless gastroscopy and colonoscopy using a 2×2 factorial design.

Official title: Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal Endoscopy: A 2×2 Factorial Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

208

Start Date

2026-06-23

Completion Date

2026-08-31

Last Updated

2026-06-29

Healthy Volunteers

No

Interventions

PROCEDURE

Pre-oxygenation Position (left lateral position)

An angle measuring device is placed beside the head of the examination bed to enable precise adjustment of the head position. Pre-oxygenation phase: Administer pure oxygen via a standardized mask with tight fit, at a flow rate of 6 L/min; instruct the patient to take deep breaths while receiving continuous oxygen for 3 minutes, maintaining the same body position throughout. If the position is altered during this phase, discontinue the procedure. Left lateral pre-oxygenation: The patient assumes a left lateral position on a horizontal bed surface with the head elevated at 0°, supported by pillows to maintain a neutral spine position and avoid excessive neck extension or flexion.

PROCEDURE

Examination Position(left lateral position )

Examination Phase: From the initiation of anesthesia and endoscope insertion until completion of the procedure, the patient's position and head-of-bed angle must remain fixed throughout; any adjustments are prohibited during this phase. If the position is altered midway through the examination, the patient will be excluded from the study. Left lateral position examination: The patient assumes a 90-degree left lateral position on a horizontal bed surface with the head of the bed elevated to 0°, supported by pillows to maintain a neutral spinal alignment, avoiding excessive neck extension or flexion.

PROCEDURE

Pre-oxygenation Position( left lateral head elevation in a 30-degree position)

An angle measuring device is placed beside the head of the examination bed to allow precise adjustment of the head position. Pre-oxygenation phase: The patient receives pure oxygen via a standardized mask with tight fit, at a flow rate of 6 L/min; they are instructed to take deep breaths while receiving continuous oxygen for 3 minutes, maintaining the same body position throughout. If the position is altered during this phase, the procedure is discontinued. Left-sided head elevation (30°): During pre-oxygenation, the patient lies in a left lateral position on a horizontal bed surface with the head elevated by 30°, supported by pillows to maintain a neutral spinal alignment and prevent excessive neck extension or flexion.

PROCEDURE

Examination Position(left lateral head elevation in a 30-degree position)

Examination Phase: From the initiation of anesthesia and endoscope insertion until completion of the procedure, the patient's position and head-of-bed angle must remain fixed throughout; any adjustments are prohibited during this phase. If the position is altered midway through the examination, the patient will be excluded from the study. Left lateral decubitus examination: The patient assumes a left lateral position on a horizontal bed surface with the head elevated at 30°, supported by a pillow to maintain a neutral spinal alignment, avoiding excessive neck extension or flexion.

Locations (1)

General hospital of Ningxia medical university

Yinchuan, Ningxia, China