Clinical Research Directory

Inclusion Criteria: 1. Patient age ≥18 years old; 2. As assessed by the cardiac team the patient needs coronary revascularization, but CABG (Coronary Artery Bypass Grafting) is of high risk, or the patient refuses to undergo CABG; 3. The patient is meeting one of the following: (1) Coronary Artery Disease and left ventricular ejection fraction ≤35%; (2) Coronary Artery Disease and left ventricular ejection fraction ≤40% and severe heart failure; 4. PCI was required for imaging diagnosis; 5. Patient willing and able to comply with protocol requirements and accept clinical follow-up; able to understand study purpose and sign informed consent. Exclusion Criteria: 1. Cardiac arrest within 24 hours; 2. The implantation of an interventional left ventricular assist system was either contraindicated or not feasible; 3. ST-segment elevation myocardial infarction (STEMI) within 24 hours; 4. Chronic Kidney Disease; 5. Severe right heart failure or severe tricuspid regurgitation; 6. Presence of abnormal coagulation parameters (platelet count ≤75,000/mm\^3, INR≥2.0, or fibrinogen ≤1.50g/L); 7. Moderate or higher anemia; 8. History of stroke or transient ischemic attack (TIA) within one month; 9. Allergy or intolerance to anticoagulants or contrast agent; 10. Active internal bleeding within a month; 11. Presence of uncontrolled active infection; 12. Pregnant or lactating women; 13. Patients are participating in other clinical trials; 14. Other circumstances that are determined by the investigator to be unsuitable for the study.