Clinical Research Directory
Browse clinical research sites, groups, and studies.
Total en Bloc Urethra Preservation at Robot-assisted Prostatectomy IDEAL Stage 2a
Sponsor: Sami-Ramzi Leyh-Bannurah
Summary
Prospective single-arm IDEAL stage 2a feasibility study of urethra-preserving RARP in localized prostate cancer.
Official title: Total en Bloc Urethra Preservation at Robot-assisted Prostatectomy (ToP-RAP): A Prospective IDEAL Stage 2a Study
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-01-30
Completion Date
2030-12-31
Last Updated
2026-07-01
Healthy Volunteers
No
Interventions
ToP-RAP
\*\*ToP-RAP\*\* is a urethra-preserving modification of robot-assisted radical prostatectomy (RARP) for localized prostate cancer. Its distinguishing feature is preservation of the \*\*entire intraprostatic urethra with complete omission of urethral transection and the vesicourethral anastomosis\*\*. This separates it mechanistically from standard RARP, Retzius-sparing RARP, and the hood and sleeve techniques - all of which transect the urethra and reconstruct a vesicourethral anastomosis - and from urethra-sparing \*simple\* prostatectomy, which is a benign (BPH) enucleation rather than whole-gland cancer surgery. The whole prostatic gland is removed while only the intraprostatic urethra is retained, with anterolateral neurovascular-bundle preservation.
Locations (2)
Clinic Bel Etage
Düsseldorf, Germany
Diakonie Klinikum Jung-Stilling
Siegen, Germany