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COMPLETED
NCT07680036
NA

Resistance Training and Capillarization - Role on the Anabolic Response in Older Adults

Sponsor: University of Padova

View on ClinicalTrials.gov

Summary

Ecco una versione strutturata secondo il template ClinicalTrials.gov: The goal of this clinical trial is to learn how muscle capillaries influence the response to resistance exercise training in older adults. The study will include older men and women who may experience age-related declines in muscle mass and function. The main questions it aims to answer are: * Does baseline muscle capillarization influence the increase in muscle size and function following resistance exercise training? * Can resistance exercise stimulate the formation of new capillaries in older adults with lower baseline capillarization, and how is this related to muscle growth? Participants will: * Undergo assessments of muscle structure, capillarization, and physical function before and after the intervention. * Participate in a supervised resistance exercise training program. * Provide muscle samples and other physiological measurements to evaluate changes in muscle growth and blood vessel formation. Researchers will analyze the relationship between baseline muscle capillarization, exercise-induced angiogenesis, and improvements in muscle mass and function to better understand why some older adults respond more effectively to resistance exercise than others.

Official title: RESISTANCE TRAINING AND CAPILLARIZATION - ROLE ON THE ANABOLIC RESPONSE IN OLDER ADULTS

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2024-01-01

Completion Date

2026-05-31

Last Updated

2026-07-01

Healthy Volunteers

Yes

Interventions

OTHER

Exercise

2 months of different combination of aerobic and resistance training before undergoing to 1 month of resistance training at 80% 1RM

Locations (1)

Nutrition and Exercise Lab, DSB

Padova, PD, Italy