Clinical Research Directory
Browse clinical research sites, groups, and studies.
Resistance Training and Capillarization - Role on the Anabolic Response in Older Adults
Sponsor: University of Padova
Summary
Ecco una versione strutturata secondo il template ClinicalTrials.gov: The goal of this clinical trial is to learn how muscle capillaries influence the response to resistance exercise training in older adults. The study will include older men and women who may experience age-related declines in muscle mass and function. The main questions it aims to answer are: * Does baseline muscle capillarization influence the increase in muscle size and function following resistance exercise training? * Can resistance exercise stimulate the formation of new capillaries in older adults with lower baseline capillarization, and how is this related to muscle growth? Participants will: * Undergo assessments of muscle structure, capillarization, and physical function before and after the intervention. * Participate in a supervised resistance exercise training program. * Provide muscle samples and other physiological measurements to evaluate changes in muscle growth and blood vessel formation. Researchers will analyze the relationship between baseline muscle capillarization, exercise-induced angiogenesis, and improvements in muscle mass and function to better understand why some older adults respond more effectively to resistance exercise than others.
Official title: RESISTANCE TRAINING AND CAPILLARIZATION - ROLE ON THE ANABOLIC RESPONSE IN OLDER ADULTS
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-01-01
Completion Date
2026-05-31
Last Updated
2026-07-01
Healthy Volunteers
Yes
Conditions
Interventions
Exercise
2 months of different combination of aerobic and resistance training before undergoing to 1 month of resistance training at 80% 1RM
Locations (1)
Nutrition and Exercise Lab, DSB
Padova, PD, Italy