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Propofol-sevoflurane Induction for Pediatric Nasotracheal Intubation.
Sponsor: Bezmialem Vakif University
Summary
Pediatric anesthesia differs significantly from adult anesthesia due to physiological differences and increased sensitivity to anesthetic agents. In surgeries requiring nasotracheal intubation, such as dental and maxillofacial procedures, achieving optimal intubation conditions while minimizing pharmacological exposure is of considerable importance. The combination of propofol and sevoflurane is frequently preferred in pediatric anesthesia because it provides rapid induction and stable hemodynamic conditions. Therefore, this randomized controlled trial aims to evaluate nasotracheal intubation conditions following propofol-sevoflurane induction with reduced pharmacological exposure in pediatric patients. The study is expected to contribute to clinical practice by enhancing patient safety while reducing anesthetic drug use.
Official title: Nasotracheal Intubating Conditions With Reduced Pharmacologic Exposure After Propofol-sevoflurane Induction in Pediatric Parients: a Randomized Contolled Trial
Key Details
Gender
All
Age Range
1 Year - 10 Years
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2026-07-01
Completion Date
2026-08-01
Last Updated
2026-07-02
Healthy Volunteers
No
Conditions
Interventions
reduced pharmacologic exposure
patients in group R will undergo combination of sevoflurane and propofol only anesthesia induction
conventional anesthetic induction
in group C, conventional anesthetic regimen will be used for anesthesia induction