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An Exploratory Study of Personalized Cancer Vaccine in Adjuvant Therapy of Solid Tumors
Sponsor: Ruijin Hospital
Summary
The purpose of this study is to evaluate the safety and tolerability of ABO2109 in combination with toripalimab, and to evaluate the immunogenicity, pharmacokinetics, pharmacodynamics, as well as biomarker characteristics of the investigational cancer vaccine. In addition, the antitumor activity of ABO2109 will be assessed during both dose exploration and expansion stages, the accumulative data will support the clinical development of ABO2109.
Official title: An Exploratory Study of Personalized Cancer Vaccine (ABO2109) in Adjuvant Therapy of Solid Tumors
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-06-09
Completion Date
2031-02-09
Last Updated
2026-07-02
Healthy Volunteers
No
Conditions
Interventions
ABO2109 Injection
personalized cancer vaccine
Toripalimab
Anti-PD-1 monoclonal antibody
Locations (1)
Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China