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RECRUITING
NCT07680582
EARLY_PHASE1

An Exploratory Study of Personalized Cancer Vaccine in Adjuvant Therapy of Solid Tumors

Sponsor: Ruijin Hospital

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate the safety and tolerability of ABO2109 in combination with toripalimab, and to evaluate the immunogenicity, pharmacokinetics, pharmacodynamics, as well as biomarker characteristics of the investigational cancer vaccine. In addition, the antitumor activity of ABO2109 will be assessed during both dose exploration and expansion stages, the accumulative data will support the clinical development of ABO2109.

Official title: An Exploratory Study of Personalized Cancer Vaccine (ABO2109) in Adjuvant Therapy of Solid Tumors

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-06-09

Completion Date

2031-02-09

Last Updated

2026-07-02

Healthy Volunteers

No

Conditions

Interventions

DRUG

ABO2109 Injection

personalized cancer vaccine

DRUG

Toripalimab

Anti-PD-1 monoclonal antibody

Locations (1)

Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, China