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A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Sponsor: Bristol-Myers Squibb
Summary
The purpose of this study is to assess the safety, tolerability, and efficacy of Imzokitug in combination with Pumitamig and Platinum-Doublet Chemotherapy (PDCT) versus Pumitamig and PDCT as first-line treatment for participants with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Official title: A Phase 2, Randomized, Open-label, Study Assessing the Safety, Tolerability and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2026-08-15
Completion Date
2030-09-15
Last Updated
2026-07-02
Healthy Volunteers
No
Conditions
Interventions
Pumitamig
Specified dose on specified days
Imzokitug
Specified dose on specified days
Locations (71)
Local Institution - 0170
Athens, Georgia, United States
Local Institution - 0034
Lexington, Kentucky, United States
Local Institution - 0171
Lexington, Kentucky, United States
Local Institution - 0123
Baltimore, Maryland, United States
Local Institution - 0102
Omaha, Nebraska, United States
Local Institution - 0080
New York, New York, United States
Local Institution - 0105
Nashville, Tennessee, United States
Local Institution - 0095
Houston, Texas, United States
Local Institution - 0135
Madison, Wisconsin, United States
Local Institution - 0092
Viedma, Río Negro Province, Argentina
Local Institution - 0082
Rosario, Santa Fe Province, Argentina
Local Institution - 0094
Buenos Aires, Argentina
Local Institution - 0074
Gosford, New South Wales, Australia
Local Institution - 0134
Westmead, New South Wales, Australia
Local Institution - 0167
Greenslopes, Queensland, Australia
Local Institution - 0100
Heidelberg, Victoria, Australia
Local Institution - 0048
Perth, Western Australia, Australia
Local Institution - 0003
Natal/RN, Rio Grande do Norte, Brazil
Local Institution - 0006
Porto Alegre, Rio Grande do Sul, Brazil
Local Institution - 0005
Barretos, São Paulo, Brazil
Local Institution - 0001
São Paulo, Brazil
Local Institution - 0081
Santiago, Santiago Metropolitan, Chile
Local Institution - 0149
Santiago, Santiago Metropolitan, Chile
Local Institution - 0084
Viña del Mar, Valparaiso, Chile
Local Institution - 0038
Beijing, Beijing Municipality, China
Local Institution - 0138
Fuzhou, Fujian, China
Local Institution - 0050
Wuhan, Hubei, China
Local Institution - 0147
Nanjing, Jiangsu, China
Local Institution - 0140
Shanghai, Shanghai Municipality, China
Local Institution - 0169
Shanghai, Shanghai Municipality, China
Local Institution - 0144
Chengdu, Sichuan, China
Local Institution - 0139
Hangzhou, Zhejiang, China
Local Institution - 0137
Hangzhou, Zhejiang, China
Local Institution - 0168
Hangzhou, Zhejiang, China
Local Institution - 0131
Nice, Alpes-Maritimes, France
Local Institution - 0110
Marseille, Bouches-du-Rhône, France
Local Institution - 0087
Montpellier, Languedoc-Roussillon, France
Local Institution - 0119
Villejuif, Val-de-Marne, France
Local Institution - 0047
Grenoble, France
Local Institution - 0109
Paris, France
Local Institution - 0085
Saint-Herblain, France
Local Institution - 0019
Paris, Île-de-France Region, France
Local Institution - 0126
Stuttgart, Baden-Wurttemberg, Germany
Local Institution - 0156
Marburg, Hesse, Germany
Local Institution - 0152
Homburg, Saarland, Germany
Local Institution - 0065
Cologne, Germany
Local Institution - 0042
Haile, Germany
Local Institution - 0125
Hessen, Germany
Local Institution - 0128
Misterbianco, Catania, Italy
Local Institution - 0043
Bari, Italy
Local Institution - 0148
Bergamo, Italy
Local Institution - 0159
Milan, Italy
Local Institution - 0014
Ravenna, Italy
Local Institution - 0011
Rozzano (MI), Italy
Local Institution - 0114
Florești, Cluj, Romania
Local Institution - 0113
Timișoara, Timiș County, Romania
Local Institution - 0076
Bucharest, Romania
Local Institution - 0008
Cluj-Napoca, Romania
Local Institution - 0075
Craiova, Romania
Local Institution - 0115
Iași, Romania
Local Institution - 0116
Iași, Romania
Local Institution - 0132
Badalona, Barcelona, Spain
Local Institution - 0162
Seville, Seville, Spain
Local Institution - 0027
Barcelona, Spain
Local Institution - 0068
Barcelona, Spain
Local Institution - 0163
Barcelona, Spain
Local Institution - 0041
Madrid, Spain
Local Institution - 0010
Majadahonda, Spain
Local Institution - 0020
Málaga, Spain
Local Institution - 0035
London, Greater London, United Kingdom
Local Institution - 0037
Guildford, United Kingdom