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LRRK2 (Leucine-Rich Repeat Kinase 2) Parkinson's Disease Fingerprint
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Summary
The goal of this interventional monocentric study is to identify molecular and clinical markers of LRRK2-related Parkinson's disease through blood markers analysis and deep clinical phenotyping. Patients who meet the inclusion criteria, after signing the informed consent form will be clinically evaluated by a neurologist expert in movement disorders. Eventually, patients will undergo a blood sample collection, a brain MRI, and a high density EEG. All data will be collected using an ad hoc electronic Case Report Form (CRF) developed for the study
Official title: LRRK2 Associated Parkinson's Disease: Definition of a Clinical, Molecular and Neurophysiological Fingerprint
Key Details
Gender
All
Age Range
30 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-09-01
Completion Date
2029-09-01
Last Updated
2026-07-10
Healthy Volunteers
No
Conditions
Interventions
The interventions of the study are the study of blood biomarkers and neuroimaging and neurophysiological data
* Blood sample collection and markers analysis * Brain 1.5 T MRI * High density EEG