Clinical Research Directory

Inclusion Criteria: Patients with a diagnosis of Type 2 diabetes (T2D) mellitus * Ages equal or greater 18 years ("age" determined at the time of the Screening Visit) * Bodyweight between 30-450 kg * Comfortable with and willing to administer basal insulin injections, once a day, for approximately 75 consecutive days, and log daily injections in the Dexcom CGM mobile application. * Willing to wear Dexcom CGM for duration of study Exclusion Criteria: * Recent severe hypoglycemia, complicated by seizure(s) or loss of consciousness, in the past 3 months * Subjects with any contraindications for starting or continuing basal insulin therapy * Glomerular filtration rate (eGFR) \< 30 ml/min/1.73m2 (within 6 months of insertion) or on hemodialysis * Introducing or increasing glucose lowering medications simultaneously * Any condition that, in the opinion of the Investigator, would interfere with a subject's participation in the trial or pose excessive risk to subject and/or study staff * For subjects of child-bearing potential: Pregnancy, demonstrated by a positive test no more than 72 hours prior to Clinic Visit 1 * Has used prandial insulin in the last 30 days. * Anticipated addition of medications that could have significant impact on insulin sensitivity such as atypical antipsychotics.