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Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training
Sponsor: The Cleveland Clinic
Summary
A research study to assess the baseline olfactory function, mental health status, clinical severity, and immunological profile in patients with smell loss. The impact of a 3-month olfactory training program on smell function, immunological changes, and mental health in patients with smell loss will be evaluated. The primary purpose of this study is to investigate tissue and blood samples to identify molecules that may be related to smell loss, ultimately aiming to develop future treatments for this condition and correlate with cognition.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
52
Start Date
2025-12-09
Completion Date
2027-03-31
Last Updated
2026-07-02
Healthy Volunteers
Yes
Conditions
Interventions
Smell Training
Patients experiencing loss of smell from chronic rhinosinusitis (CRS)will undergo smell training.
Locations (1)
The Cleveland Clinic
Cleveland, Ohio, United States