Clinical Research Directory
Browse clinical research sites, groups, and studies.
EFFECT OF PLATELET CONCENTRATE TRANSFUSION ON MICROCIRCULATORY ENDOTHELIAL FUNCTION IN INTENSIVE CARE UNIT
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
This study aims to investigate the impact of platelet concentrate (PC) transfusions on endothelial function and the systemic inflammatory response in thrombopenic patients admitted to intensive care who require prophylactic platelet transfusions. Endothelial function will be measured using a laser Doppler device coupled with an acetylcholine iontophoresis system that is applied to the skin.
Official title: EFFECT OF PLATELET CONCENTRATE TRANSFUSION ON MICROCIRCULATORY ENDOTHELIAL FUNCTION IN INTENSIVE CARE UNIT.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2026-07
Completion Date
2027-07
Last Updated
2026-07-02
Healthy Volunteers
No
Locations (1)
Medical Intensive Care Unit, Saint-Antoine Hospital, AP-HP, Paris, France
Paris, France