Clinical Research Directory

Inclusion Criteria: * Age requirement: 0 to \< 18 years. * For children under 15 years old: Has a guardian or other legal representative who is able to provide consent of a guardian OR * For children between the age of 15-17 years; able to provide written consent form and the legal guardians can be reached to be informed of the study participation. * Have an upper limb (right OR left side) that fits the cuff size of the device (circumference ranging 3 cm to 33 cm) OR have a thigh (right OR left side) that fits a cuff size of the device (circumference ranging 38 to 50 cm). * Have an arterial line as a standard of care, which measures invasive blood pressure. * Expected to remain in the unit for the duration of the study procedure. Exclusion Criteria: * Have previously participated in this study (no subject may participate more than once). * Subjects with peripheral arterial diseases (causing left/right arm difference). * Hemodynamically unstable subjects Subjects with complications on vasoactive agents at discretion of the Investigator. * Exhibited injuries, deformities, intravenous lines, or other abnormalities that, in the opinion of the Investigator, may prevent proper cuff application or functioning. * Are suffering from infection(s) or immunocompromised subjects that require isolation. * For adolescents of child-bearing potential, who are currently pregnant, suspected to be pregnant, or are currently lactating. * PI, designee or caring physician decision due to subject health conditions