Clinical Research Directory

Inclusion Criteria * Age 18 years or older. * Biopsy-confirmed localized prostate adenocarcinoma. * Treated with nerve-sparing radical prostatectomy, radiotherapy, or cryoablation as primary index therapy for prostate cancer at Duke Health. * Initiating pelvic floor physical therapy as part of routine clinical care. * Pre-treatment International Index of Erectile Function-5 (IIEF-5) score meeting the eligibility threshold, with or without aids, determined by medical record chart review (when documented within 4 months prior to index treatment) or collected post-treatment with participant recall anchored to the month prior to treatment. Eligibility threshold for the IIEF-5 is at or above 17. * Able to read and understand English to complete patient-reported outcome measures. * Ability to provide informed consent. Exclusion Criteria * Any androgen deprivation therapy (ADT) given for prostate cancer treatment or planned during the intervention or follow-up period, including neoadjuvant, concurrent, or adjuvant ADT. * Recieved non-nerve-sparing treatment (when applicable). * Unable to engage in pelvic floor physical therapy or penile rehabilitation protocol. * Need for additional or secondary prostate cancer treatment during the intervention period. * Documented cognitive impairment or impairment that would interfere with participation. * Major psychiatric concern that would interfere with ability to consent or participate, such as schizophrenia, based on the medical record or treating clinician assessment. * Inability to complete study video visits or questionnaires. * History of prior local or systemic treatment for prostate cancer