Clinical Research Directory

Inclusion Criteria: * Diagnosis of arrhythmogenic cardiomyopathy, including right-dominant arrhythmogenic right ventricular cardiomyopathy, biventricular arrhythmogenic cardiomyopathy, or left-dominant arrhythmogenic left ventricular cardiomyopathy. * ICD implantation. * Documented sustained ventricular tachyarrhythmia, including polymorphic ventricular tachycardia, ventricular fibrillation, or monomorphic ventricular tachycardia. * Periodic clinical and ICD follow-up. * Arrhythmia onset available from ICD electrograms and/or ECG recordings. * ECG/EGM tracings available for analysis by the steering ECG committee. Exclusion Criteria: * Incomplete ICD data or incomplete ICD follow-up. * Significant coronary artery disease, defined as coronary plaque greater than 50% at coronary angiography or coronary computed tomography angiography. * Primary valvular heart disease or congenital heart disease. * Infiltrative or inflammatory cardiomyopathies, including sarcoidosis or amyloidosis. * Previous exposure to therapies associated with cardiac toxicity, including chemotherapy.